Serum’s HPV vaccine non-inferior to Gardasil

News Excerpt:
Serum Institute's Cervavac, a quadrivalent HPV vaccine, found safe and comparable to Gardasil in a phase-2/3 trial in India.

About the news:

  • The trial found that two doses of the Serum’s Cervavac vaccine generated nearly double the antibody response against HPV subtypes compared with the response generated with Gardasil vaccine.
  • The study focused on adolescents, as the effectiveness of the HPV vaccine tends to be higher when administered at a younger age.
  • Serum's vaccine was evaluated based on WHO's recommendations, using an immunobridging approach, comparing immune responses with the efficacy-proven population of women aged 15-26 who received Gardasil.

Human papillomavirus (HPV): 

  • It is a common sexually transmitted infection (STI).
  •  HPV often has no symptoms and goes away by itself, but HPV can sometimes cause serious illness. Symptoms may include warts on the genitals or surrounding skin.
  • There is no treatment or cure for HPV. This is why it is important to have the HPV vaccination. 

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